Xr_3da exe has stopped working

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Please let me know if I can provide any additional information. The version installed by the HijackThis installer in C:\Program Files\Trend Micro\HijackThis, which should be the same, is 396,288 bytes. My latest attempt to run HijackThis used a copy of the executable downloaded on a different machine and burned to a CD using the links in this forum. These symptoms have persisted for several days.

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Windows Defender definition update fails with error code 0x80244019. Windows Update fails with error 80244019 ('Windows Update encountered an unknown error')

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McAfee AV update failed until hosts file was manually edited Windows Defender scans in normal mode, detects hosts file edits McAfee AV runs in safe mode, detects and claims to fix two 'rootkit' issues, which reappear the next time it runs McAfee AV runs in normal mode, detects nothing ERUNT failed to install first time, succeeded and reported successful backup second time HijackThis 2.0.0.2 will not run in normal or safe modes SpyBot S&D 1.62 will not run in normal or safe modes Firefox quick search box redirects to fake search results page blocked (same workaround does not work)

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blocked (worked around by manually editing hosts) My computer has recently acquired a malware infection that is affecting multiple anti-virus, anti-spyware and system maintenance sites and tools: